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Immune Dysfunction and ASD

Cytokines are part of our complex immune system and have been studied in relation to autism.  Researchers measured cytokine release in children with autism (ASD), typically-developing children (TD) and those with non-autistic developmental disabilities ( subjects were age-matched, 2-5yrs).  Findings indicate a significant increase in plasma levels of cytokines in the ASD group compared with TD subjects and that it was most striking in the children with regressive autism.

 

The researchers conclude that inflammatory responses may be linked to disturbances in the behaviour of autistic children and could have implications for diagnosis as well as therapeutic strategies.

 

Posted: 9th February 2011

Source:  Brain Behaviour and Immunity Jan 2011 25 (1) p 40-45

Link: http://www.ncbi.nlm.nih.gov/pubmed/20705131  

 
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